发明申请
US20060121054A1 Electroporation of mycobacterium and overexpression of antigens in mycobacteria
有权
分枝杆菌的电穿孔和抗原在分枝杆菌中的过表达
- 专利标题： Electroporation of mycobacterium and overexpression of antigens in mycobacteria
- 专利标题（中）： 分枝杆菌的电穿孔和抗原在分枝杆菌中的过表达
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申请号： US11288424申请日： 2005-11-29
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公开(公告)号： US20060121054A1公开(公告)日： 2006-06-08
- 发明人: Ronggai Sun , David Hone , Jerald Sadoff
- 申请人： Ronggai Sun , David Hone , Jerald Sadoff
- 主分类号： A61K39/02
- IPC分类号： A61K39/02 ; A61K39/04 ; C12N1/21
摘要：
Recombinant Mycobacterium strains with improved vaccinal properties for use as vaccinating agents are provided. The parent strains of the recombinant Mycobacterium strains are selected for their potent immunogenicity. The Mycobacterium strains do not display antibiotic resistance, and do not exhibit horizontal transfer to gram-negative bacteria.
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