发明申请
US20060122151A1 Composition containing an association of aspirin and an anti-Xa oligosaccharide and use of an anti-Xa oligosaccharide optionally in combination with aspirin
审中-公开
含有阿斯匹林和抗Xa寡糖的组合的组合物和任选与阿司匹林组合的抗Xa寡糖的用途
- 专利标题： Composition containing an association of aspirin and an anti-Xa oligosaccharide and use of an anti-Xa oligosaccharide optionally in combination with aspirin
- 专利标题（中）： 含有阿斯匹林和抗Xa寡糖的组合的组合物和任选与阿司匹林组合的抗Xa寡糖的用途
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申请号： US11269893申请日： 2005-11-09
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公开(公告)号： US20060122151A1公开(公告)日： 2006-06-08
- 发明人: Roger Cariou
- 申请人： Roger Cariou
- 专利权人： Sanofi-Synthelabo,Akzo Nobel NV.
- 当前专利权人： Sanofi-Synthelabo,Akzo Nobel NV.
- 主分类号： A61K31/737
- IPC分类号： A61K31/737 ; A61K31/60
摘要：
The invention relates to the use of a synthetic oligosaccharide which is a selective inhibitor of factor Xa acting via antithrombin III, alone or in association with aspirin, for the preparation of medicaments intended for preventing or treating thromboembolic diseases occurring in a mammal which has undergone a percutaneous transluminal angioplasty. The subject of the invention is moreover pharmaceutical compositions for the treatment or prophylaxy of thromboembolic diseases occurring in a mammal which has undergone a percutaneous transluminal angioplasty, comprising the association of an effective quantity of at least one synthetic oligosaccharide, which is a selective inhibitor of factor Xa acting via antithrombin III, and of an effective quantity of aspirin, optionally mixed with one or more pharmaceutically acceptable excipients.
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