发明申请
US20060128695A1 Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses
审中-公开
环核苷酸磷酸二酯酶抑制剂，制备及用途
- 专利标题： Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses
- 专利标题（中）： 环核苷酸磷酸二酯酶抑制剂，制备及用途
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申请号： US10533157申请日： 2003-10-30
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公开(公告)号： US20060128695A1公开(公告)日： 2006-06-15
- 发明人: Jean-Jacques Bourguignon , Claire Lugnier , Mustapha Abarghaz , Yan Lagouge , Patrick Wagner , Cesare Mondadori , Jean-Paul Macher , Dominique Schultz , Pierre Raboisson
- 申请人： Jean-Jacques Bourguignon , Claire Lugnier , Mustapha Abarghaz , Yan Lagouge , Patrick Wagner , Cesare Mondadori , Jean-Paul Macher , Dominique Schultz , Pierre Raboisson
- 申请人地址： FR Mulhouse FR Strasbourg
- 专利权人： NEURO3D,UNIVERSITE LOUIS PASTEUR
- 当前专利权人： NEURO3D,UNIVERSITE LOUIS PASTEUR
- 当前专利权人地址： FR Mulhouse FR Strasbourg
- 优先权： FR02/13607 20021030
- 国际申请： PCT/FR03/03247 WO 20031030
- 主分类号： A61K31/5513
- IPC分类号： A61K31/5513 ; C07D403/02 ; C07D243/12
摘要：
The invention concerns the use of PDE2 inhibitors for treating disorders of the central and peripheral nervous system, a method for therapeutic treatment by administering to an animal said inhibitors. More specifically, the invention concerns novel benzodiazepinone derivatives and their uses in therapeutics more particularly for treating pathologies involving activity of a cyclic nucleotide phosphodiesterase type 2. The invention also concerns methods for preparing same and novel synthesis intermediates.
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