发明申请
- 专利标题： Methods and compositions for RNA interference
- 专利标题（中）： RNA干扰的方法和组成
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申请号： US10997086申请日： 2004-11-23
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公开(公告)号： US20060135456A1公开(公告)日： 2006-06-22
- 发明人: Gregory Hannon , Patrick Paddison , Despina Siolas
- 申请人： Gregory Hannon , Patrick Paddison , Despina Siolas
- 主分类号： A61K48/00
- IPC分类号： A61K48/00
摘要：
The present invention provides methods for attenuating gene expression in a cell, especially in a mammalian cell, using gene-targeted double stranded RNA (dsRNA), such as a hairpin RNA. The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene).
公开/授权文献
- US08202846B2 Methods and compositions for RNA interference 公开/授权日：2012-06-19
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