发明申请
US20060141606A1 Enantioconvergent chemoenzymatic synthesis of (R)-gamma-amino-beta-hydroxybutyric acid ((R)-GABOB)
有权
（R） - 氨基-β-羟基丁酸（（R）-GABOB）的光化学转化化学酶合成
- 专利标题： Enantioconvergent chemoenzymatic synthesis of (R)-gamma-amino-beta-hydroxybutyric acid ((R)-GABOB)
- 专利标题（中）： （R） - 氨基-β-羟基丁酸（（R）-GABOB）的光化学转化化学酶合成
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申请号： US11022275申请日： 2004-12-23
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公开(公告)号： US20060141606A1公开(公告)日： 2006-06-29
- 发明人: Ahmed Kamal , Gollapalli Khanna , Krishnaji Tadiparthi , Ramu Rondla
- 申请人： Ahmed Kamal , Gollapalli Khanna , Krishnaji Tadiparthi , Ramu Rondla
- 申请人地址： IN New Delhi
- 专利权人： Council of Scientific and Industrial Research
- 当前专利权人： Council of Scientific and Industrial Research
- 当前专利权人地址： IN New Delhi
- 主分类号： C12P41/00
- IPC分类号： C12P41/00
摘要：
The present invention particularly relates to a chemoenzymatic process for the stereoselective preparation of both enantiomers of 3-hydroxy-4-trityloxy butanenitrile key intermediates for the preparation of (R)-GABOB by lipase mediated kinetic resolution of its racemates and their effective application in the enantioconvergent synthesis of (R)-GABOB.
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