发明申请
US20060148843A1 Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof
有权
抑制香草素受体亚型1（VR1）的噻吩并吡啶基化合物及其用途
- 专利标题： Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof
- 专利标题（中）： 抑制香草素受体亚型1（VR1）的噻吩并吡啶基化合物及其用途
-
申请号： US11293012申请日： 2005-12-02
-
公开(公告)号： US20060148843A1公开(公告)日： 2006-07-06
- 发明人: Sean Turner , Tammie Jinkerson , Arthur Gomtsyan , Chih-Hung Lee
- 申请人： Sean Turner , Tammie Jinkerson , Arthur Gomtsyan , Chih-Hung Lee
- 主分类号： A61K31/4743
- IPC分类号： A61K31/4743 ; C07D498/02
摘要：
The present invention discloses fused thienopyridyl compounds of general formula (I) wherein X1-X6, R5-R7, Z1 and L are as defined in the description. The resent invention also discloses a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain, urinary incontinence, bladder overactivity, and inflammatory thermal hyperalgesia in mammals, and pharmaceutical compositions including those compounds.
公开/授权文献
信息查询
IPC分类:
