发明申请
US20060148850A1 4-{'3-(Sulfonylamino) phenyl!'1-(cyclymethyl) piperidin-4-ylidene! methyl}benazmide derivativess as delta opioid receptor ligands for the treatment of pain, anxiety and functional gastrointestinal disorder
审中-公开
4 - {'3-（磺酰基氨基）苯基''1-（环甲基）哌啶-4-亚基 甲基} benazmide衍生为δ阿片受体配体，用于治疗疼痛，焦虑和功能性胃肠道疾病
- 专利标题： 4-{'3-(Sulfonylamino) phenyl!'1-(cyclymethyl) piperidin-4-ylidene! methyl}benazmide derivativess as delta opioid receptor ligands for the treatment of pain, anxiety and functional gastrointestinal disorder
- 专利标题（中）： 4 - {'3-（磺酰基氨基）苯基''1-（环甲基）哌啶-4-亚基 甲基} benazmide衍生为δ阿片受体配体，用于治疗疼痛，焦虑和功能性胃肠道疾病
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申请号： US10541664申请日： 2004-01-13
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公开(公告)号： US20060148850A1公开(公告)日： 2006-07-06
- 发明人: William Brown , Andrew Griffin , Christopher Walpole
- 申请人： William Brown , Andrew Griffin , Christopher Walpole
- 申请人地址： SE Sodertalje SE-151 85
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje SE-151 85
- 优先权： SE0300104-7 20030116
- 国际申请： PCT/GB04/00061 WO 20040113
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; A61K31/454 ; C07D211/68
摘要：
Compounds of general formula: (I) wherein R1, R2, R3, R4 and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.