发明申请
- 专利标题: Phthalazinone derivatives
- 专利标题(中): 酞嗪衍生物
-
申请号: US11318155申请日: 2005-12-23
-
公开(公告)号: US20060149059A1公开(公告)日: 2006-07-06
- 发明人: Niall Martin , Graeme Smith , Stephen Jackson , Vincent Loh , Xiao-Ling Cockcroft , Ian Matthews , Keith Menear , Frank Kerrigan , Alan Ashworth
- 申请人: Niall Martin , Graeme Smith , Stephen Jackson , Vincent Loh , Xiao-Ling Cockcroft , Ian Matthews , Keith Menear , Frank Kerrigan , Alan Ashworth
- 申请人地址: GB Cambridge GB Cornwall
- 专利权人: Kudos Pharmaceuticals Limited,Maybridge Limited
- 当前专利权人: Kudos Pharmaceuticals Limited,Maybridge Limited
- 当前专利权人地址: GB Cambridge GB Cornwall
- 优先权: GB0305681.9 20030312
- 主分类号: C07D403/02
- IPC分类号: C07D403/02 ; A61K31/502
摘要:
Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.
公开/授权文献
- US07662818B2 Phthalazinone derivatives 公开/授权日:2010-02-16
信息查询