Invention Application
- Patent Title: Phthalazinone derivatives
- Patent Title (中): 酞嗪衍生物
-
Application No.: US11318155Application Date: 2005-12-23
-
Publication No.: US20060149059A1Publication Date: 2006-07-06
- Inventor: Niall Martin , Graeme Smith , Stephen Jackson , Vincent Loh , Xiao-Ling Cockcroft , Ian Matthews , Keith Menear , Frank Kerrigan , Alan Ashworth
- Applicant: Niall Martin , Graeme Smith , Stephen Jackson , Vincent Loh , Xiao-Ling Cockcroft , Ian Matthews , Keith Menear , Frank Kerrigan , Alan Ashworth
- Applicant Address: GB Cambridge GB Cornwall
- Assignee: Kudos Pharmaceuticals Limited,Maybridge Limited
- Current Assignee: Kudos Pharmaceuticals Limited,Maybridge Limited
- Current Assignee Address: GB Cambridge GB Cornwall
- Priority: GB0305681.9 20030312
- Main IPC: C07D403/02
- IPC: C07D403/02 ; A61K31/502

Abstract:
Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.
Public/Granted literature
- US07662818B2 Phthalazinone derivatives Public/Granted day:2010-02-16
Information query