发明申请
- 专利标题： Modulating nuclear receptor coactivator binding
- 专利标题（中）： 调节核受体共激活因子结合
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申请号： US11274682申请日： 2005-11-14
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公开(公告)号： US20060149521A1公开(公告)日： 2006-07-06
- 发明人: John Baxter , Beatrice Darimont , Weijun Feng , Robert Fletterick , Peter Kushner , Richard Wagner , Brian West , Keith Yamamoto
- 申请人： John Baxter , Beatrice Darimont , Weijun Feng , Robert Fletterick , Peter Kushner , Richard Wagner , Brian West , Keith Yamamoto
- 专利权人： Regents of the University of California
- 当前专利权人： Regents of the University of California
- 主分类号： C07K14/72
- IPC分类号： C07K14/72 ; G06G7/48
摘要：
The present invention comprises cocrystal of a nuclear receptor comprising a molecule bound to the coactivator binding site of said nuclear receptor. The present invention further comprises a machine-readable data storage medium encoded with machine readable data corresponding to the structure coordinates of amino acids of a nuclear receptor coactivator binding site which, when using a machine programmed with instructions for using said data, is capable of displaying a graphical three-dimensional representation of a molecular complex of a compound bound to a nuclear receptor coactivator binding site.
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