- 专利标题： Canine rankl and methods for preparing and using the same
- 专利标题（中）： 犬类及其使用方法
-
申请号： US10537864申请日： 2003-12-10
-
公开(公告)号： US20060154858A1公开(公告)日： 2006-07-13
- 发明人: Jeanine Mattson , Terrill McClanahan
- 申请人： Jeanine Mattson , Terrill McClanahan
- 国际申请： PCT/US03/39292 WO 20031210
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C07K16/28 ; A61K38/17 ; C07H21/04 ; C12P21/06
摘要：
The present invention provides isolated nucleic acid molecules that encode a substantial part of canine RANKL polypeptide, including the extracellular domains of that polypeptide, the polypeptide and fragments thereof. Vectors and host cells encoding and expressing canine RANKL polypeptide are provided, as well as antibodies that bind to RANKL and that inhibit RANKL activity. Also provided are methods of treating an animal to inhibit or treat the loss of bone minerals.
公开/授权文献
- US07462700B2 Canine RANKL and methods for preparing and using the same 公开/授权日：2008-12-09