发明申请
US20060166884A1 Purified rhlGF-I/rhlGFBP-3 complexes and their method of manufacture
有权
纯化的rhlGF-I / rhlGFBP-3复合物及其制备方法
- 专利标题： Purified rhlGF-I/rhlGFBP-3 complexes and their method of manufacture
- 专利标题（中）： 纯化的rhlGF-I / rhlGFBP-3复合物及其制备方法
-
申请号： US11311633申请日： 2005-12-20
-
公开(公告)号： US20060166884A1公开(公告)日： 2006-07-27
- 发明人: Mark Sleevi , Glen Kelley
- 申请人： Mark Sleevi , Glen Kelley
- 专利权人： Insmed Incorporated
- 当前专利权人： Insmed Incorporated
- 主分类号： A61K38/30
- IPC分类号： A61K38/30
摘要：
Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes.