发明申请
- 专利标题: Methods for reducing amyloid beta levels
- 专利标题(中): 降低淀粉样蛋白β水平的方法
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申请号: US11344973申请日: 2006-02-01
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公开(公告)号: US20060172964A1公开(公告)日: 2006-08-03
- 发明人: Rudolph Tanzi , Zhongcong Xie
- 申请人: Rudolph Tanzi , Zhongcong Xie
- 主分类号: A61K48/00
- IPC分类号: A61K48/00
摘要:
The present invention relates to the treatment and prophylactic prevention of Alzheimer's disease. More specifically, the present invention relates to methods and compositions for reducing production of β amyloid by reducing or preventing the binding of amyloid precursor protein (APP) to an X11 adaptor protein. Also provided are methods for identifying molecules that modulate APP-X11 binding.