发明申请
- 专利标题: Spirocvclic piperidines as mch1 antagonists and uses thereof
- 专利标题(中): 作为mch1拮抗剂的西吡唑哌啶及其用途
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申请号: US10518939申请日: 2003-07-03
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公开(公告)号: US20060173027A1公开(公告)日: 2006-08-03
- 发明人: Mohammad Marzabadi , Yu Jiang , Kai Lu , Chien-An Chen , John De Leon , John Wetzel , Kim Andersen
- 申请人: Mohammad Marzabadi , Yu Jiang , Kai Lu , Chien-An Chen , John De Leon , John Wetzel , Kim Andersen
- 申请人地址: DK Copenhagen-Valby
- 专利权人: H. Lundbeck A/S
- 当前专利权人: H. Lundbeck A/S
- 当前专利权人地址: DK Copenhagen-Valby
- 优先权: US10/189146 20020703
- 国际申请: PCT/US03/21348 WO 20030703
- 主分类号: A61K31/4747
- IPC分类号: A61K31/4747
摘要:
This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.
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