发明申请
- 专利标题： Aptamers to von Willebrand factor and their use as thrombotic disease therapeutics
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申请号： US11222346申请日： 2005-09-07
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公开(公告)号： US20060183702A1公开(公告)日： 2006-08-17
- 发明人: John Diener , H.A. Lagasse , Claude Benedict
- 申请人： John Diener , H.A. Lagasse , Claude Benedict
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C08G63/91 ; C07H21/04
摘要：
The invention relates generally to the field of nucleic acids and more particularly to aptamers capable of binding to von Willebrand Factor useful as therapeutics in and diagnostics of thrombotic diseases and/or other diseases or disorders in which von Willebrand Factor mediated platelet aggregation has been implicated. The invention further relates to materials and methods for the administration of aptamers capable of binding to von Willebrand Factor.