发明申请
- 专利标题: Method of purifying/concentrating sugar chain with sugar chain-trapping molecule and mehtod of analyzing sugar chain structure
- 专利标题(中): 用糖链捕获分子纯化/浓缩糖链的方法和分析糖链结构的方法
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申请号: US10540723申请日: 2003-12-25
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公开(公告)号: US20060188996A1公开(公告)日: 2006-08-24
- 发明人: Shinichiro Nishimura , Kenichi Niikura , Hiroaki Nakagawa , Minenobu Okayama
- 申请人: Shinichiro Nishimura , Kenichi Niikura , Hiroaki Nakagawa , Minenobu Okayama
- 申请人地址: JP Osaka 541-0045
- 专利权人: Shionogi Co., Ltd.
- 当前专利权人: Shionogi Co., Ltd.
- 当前专利权人地址: JP Osaka 541-0045
- 优先权: JP2002-378733 20021226
- 国际申请: PCT/JP03/16841 WO 20031225
- 主分类号: G01N33/00
- IPC分类号: G01N33/00 ; C08B37/00
摘要:
The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated.
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