A portable memory storage device is disclosed where access to information on the device is granted only upon proper biometric authentication of a user. The device includes a controller, a non-volatile memory which may be a flash memory, and a biometric scanner system for controlling access to the information within the non-volatile memory. Each of the controller, non-volatile memory and biometric scanner system may be mounted in a base of the portable device, with the biometric system having an exposed surface on a top portion of the base for accepting biometric data such as a fingerprint. A cover is provided which includes a USB connector capable of mating within a USB port of the host device to establish communications between the portable and host devices. The cover also covers the exposed portion of the biometric scanner to protect the sensor when the portable memory storage device is not in use.