- 专利标题: PROCESS FOR PREPARING MACROCYCLIC COMPOUNDS
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申请号: US11276573申请日: 2006-03-06
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公开(公告)号: US20060205638A1公开(公告)日: 2006-09-14
- 发明人: Carl Busacca , Fabrice Gallou , Nizar Haddad , Azad Hossain , Suresh Kapadia , Jianxiu Liu , Chris Senanayake , Xudong Wei , Nathan Yee
- 申请人: Carl Busacca , Fabrice Gallou , Nizar Haddad , Azad Hossain , Suresh Kapadia , Jianxiu Liu , Chris Senanayake , Xudong Wei , Nathan Yee
- 申请人地址: DE Ingelheim 55216
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim 55216
- 主分类号: C07K5/12
- IPC分类号: C07K5/12 ; C07D487/04
摘要:
Disclosed is a process for preparing a macrocyclic compound of the formula (I) wherein a hydroxyl-substituted macrocyclic compound of formula (3) is reacted with a sulfonyl-substituted compound of formula QUIN: The compounds of formula (I) are potent active agents for the treatment of hepatitis C virus (HCV) infection.
公开/授权文献
- US07608614B2 Process for preparing macrocyclic compounds 公开/授权日:2009-10-27
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