发明申请
US20060205711A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
审中-公开
黄嘌呤衍生物，其制备及其作为药物组合物的用途
- 专利标题： Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
- 专利标题（中）： 黄嘌呤衍生物，其制备及其作为药物组合物的用途
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申请号： US11419756申请日： 2006-05-22
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公开(公告)号： US20060205711A1公开(公告)日： 2006-09-14
- 发明人: Frank Himmelsbach , Michael Mark , Matthias Eckhardt , Elke Langkopf , Roland Maier , Ralf Lotz
- 申请人： Frank Himmelsbach , Michael Mark , Matthias Eckhardt , Elke Langkopf , Roland Maier , Ralf Lotz
- 申请人地址： DE Ingelheim
- 专利权人： Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： DE Ingelheim
- 优先权： DE10203486 20020120; DE10140345 20010817; DE10117803 20010410; DE10109021 20010224
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/5377 ; A61K31/522 ; C07D473/02
摘要：
The present invention relates to substituted xanthines of general formula wherein R1 to R4 are defined as in claim 1, the tautomers and the stereoisomers thereof, mixtures thereof, the prodrugs and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).