发明申请
US20060205942A1 2-(2-Hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
有权
2-（2-羟基联苯-3-基）-1h - 苯并咪唑-5-甲脒衍生物作为因子viia抑制剂
- 专利标题： 2-(2-Hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
- 专利标题（中）： 2-（2-羟基联苯-3-基）-1h - 苯并咪唑-5-甲脒衍生物作为因子viia抑制剂
-
申请号： US10537115申请日： 2003-12-03
-
公开(公告)号： US20060205942A1公开(公告)日： 2006-09-14
- 发明人: Aleksandr Kolesnikov , Roopa Rai , William Shrader , Steven Torkelson , Kieron Wesson , Wendy Young
- 申请人： Aleksandr Kolesnikov , Roopa Rai , William Shrader , Steven Torkelson , Kieron Wesson , Wendy Young
- 国际申请： PCT/US03/38635 WO 20031203
- 主分类号： C07D473/10
- IPC分类号： C07D473/10 ; C07F9/6512 ; C07D403/02 ; C07D235/04
摘要：
The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.