The present invention provides an apparatus and method for use with a mass spectrometer. The invention provides a mass spectrometer system for non-pneumatic ion production, including a non-pneumatic nanospray ionization source. The nanospray ionization source has a first non-pneumatic ion spray emitter for producing ions; a conduit adjacent to the ion spray emitter, the conduit having an aperture designed for receiving ions from the ion spray emitter; a first electrode for directing the ions from the ion spray emitter toward the aperture of the capillary; and a conduit electrode for directing ions into the conduit; and detector down stream from the capillary for detecting ions produced by the non-pneumatic nanospray ionization source. The invention also provides a non-pneumatic nanospray ionization source, comprising a first non-pneumatic ion spray emitter for producing ions; a conduit adjacent to the ion spray emitter, the conduit having an aperture designed for receiving ions from the ion spray emitter; a first electrode for directing ions from the ion spray emitter toward the aperture of the conduit and a conduit electrode for directing ions into the conduit. Also disclosed is a method for producing ions using a nanospray ionization source.