- 专利标题： Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use
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申请号： US10565604申请日： 2004-07-20
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公开(公告)号： US20060211677A1公开(公告)日： 2006-09-21
- 发明人: Lin Chu , Mark Goulet , Feroze Ujjainwalla , Linda Chang , Richard Frenette , Yves Girard , Michel Therien , Dwight Macdonald , John Hutchinson
- 申请人： Lin Chu , Mark Goulet , Feroze Ujjainwalla , Linda Chang , Richard Frenette , Yves Girard , Michel Therien , Dwight Macdonald , John Hutchinson
- 国际申请： PCT/US04/23334 WO 20040720
- 主分类号： C07D471/02
- IPC分类号： C07D471/02 ; C07D215/12 ; C07D237/28 ; A61K31/50 ; A61K31/4965 ; A61K31/496 ; A61K31/501 ; A61K31/506 ; A61K31/4164 ; A61K31/4745 ; A61K31/433 ; A61K31/4245
摘要：
The instant invention provides compounds of formula: (I) which are 5-lipoxygenase activating protein inhibitors: formula (I). Compounds of formula (I) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cyto-protective agents.