发明申请
US20060229325A1 N-aryl-sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents
失效
N-芳基 - 亚磺酰亚胺取代的嘧啶作为CDK和/或VEGF抑制剂，它们的生产和用作药剂
- 专利标题： N-aryl-sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents
- 专利标题（中）： N-芳基 - 亚磺酰亚胺取代的嘧啶作为CDK和/或VEGF抑制剂，它们的生产和用作药剂
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申请号： US11386111申请日： 2006-03-22
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公开(公告)号： US20060229325A1公开(公告)日： 2006-10-12
- 发明人: Ulrich Luecking , Gerhard Siemeister , Rolf Jautelat
- 申请人： Ulrich Luecking , Gerhard Siemeister , Rolf Jautelat
- 优先权： EP05090073.7 20050323
- 主分类号： A61K31/513
- IPC分类号： A61K31/513 ; A61K31/506 ; C07D417/02
摘要：
This invention relates to pyrimidine derivatives of general formula (I) in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.
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