发明申请
- 专利标题： Combinations, methods and compositions for treating cancer
- 专利标题（中）： 用于治疗癌症的组合，方法和组合物
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申请号： US11402502申请日： 2006-04-12
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公开(公告)号： US20060235006A1公开(公告)日： 2006-10-19
- 发明人: Francis Lee , Roberto Weinmann
- 申请人： Francis Lee , Roberto Weinmann
- 主分类号： A61K31/5513
- IPC分类号： A61K31/5513
摘要：
The invention relates to a combination of BCR-ABL inhibitor, exemplified by ′N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide and/or other BCR/ABL inhibitors, and a stem cell selective cytotoxic, exemplified by (R)-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine-7-carbonitrile, hydrochloride salt, and or other stem cell cytotoxic agents, pharmaceutical compositions of the combination and to methods of using the pharmaceutical compositions in the treatment of oncological disorders.
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