Invention Application
- Patent Title: Humanised antibodies to the epidermal growth factor receptor
- Patent Title (中): 人源化抗体对表皮生长因子受体
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Application No.: US11478657Application Date: 2006-07-03
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Publication No.: US20060240003A1Publication Date: 2006-10-26
- Inventor: John Ellis , Linda Durrant
- Applicant: John Ellis , Linda Durrant
- Applicant Address: GB Nottingham
- Assignee: Scancell Limited
- Current Assignee: Scancell Limited
- Current Assignee Address: GB Nottingham
- Priority: GB0011981.8 20000519; GB0020794.4 20000824
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07H21/04 ; C12P21/06 ; C07K16/44 ; C12N5/06
Abstract:
The present invention provides a humanised form of the antibody 340 obtainable from the cell line deposited with the ECACC under accession number 97021428. Such antibodies have been found to have an increased ability to kill cells compared to the murine antibody 340. Also provided are nucleic acids encoding such antibodies, as well as the use of the antibodies in medicine, in particular in the treatment of cancer.
Information query
