发明申请
US20060240440A1 Methods and compositions for the correlation of single nucleotide polymorphisms in the vitamin k epoxide reductase gene and warfarin dosage
有权
维生素K环氧化物还原酶基因中单核苷酸多态性与华法林用量相关的方法和组成
- 专利标题： Methods and compositions for the correlation of single nucleotide polymorphisms in the vitamin k epoxide reductase gene and warfarin dosage
- 专利标题（中）： 维生素K环氧化物还原酶基因中单核苷酸多态性与华法林用量相关的方法和组成
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申请号： US10573131申请日： 2004-09-23
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公开(公告)号： US20060240440A1公开(公告)日： 2006-10-26
- 发明人: Darrel Stafford , Tao Li
- 申请人： Darrel Stafford , Tao Li
- 国际申请： PCT/US04/31481 WO 20040923
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention provides a method of identifying a human subject having increased or decreased sensitivity to warfarin, comprising detecting in the subject the presence of a single nucleotide polymorphism in the VKOR gene, wherein the single nucleotide polymorphism is correlated with increased or decreased sensitivity to warfarin, thereby identifying the subject having increased or decreased sensitivity to warfarin.
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