A method for the terminal-to-terminal direct communication in the TDMA mobile communication system includes the following steps when making use of the uplink timeslots of the normal communication: in the initial phase, a sender still transmits a signal to a receiver according to its transmission timing for the normal communication; the receiver detects signals of its surrounding terminals that are in normal communication, and selects one with the strongest power as the strongest interference signal; the receiver detects the signal from the sender and compares the arrival time of the sender's signal with that of the strongest interference signal, and thereby obtains an adjustment control instruction for the sender, and feedback the control instruction to the sender; the sender adjusts its transmission timing according to the control instruction that it receives. This invention solves the synchronization problem of the direct communication in the TDD mobile communication system.