发明申请
US20060241138A1 Heterocyclic amide derivatives for the treatment of diabetes and other diseases
审中-公开
用于治疗糖尿病等疾病的杂环酰胺衍生物
- 专利标题: Heterocyclic amide derivatives for the treatment of diabetes and other diseases
- 专利标题(中): 用于治疗糖尿病等疾病的杂环酰胺衍生物
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申请号: US11476330申请日: 2006-06-28
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公开(公告)号: US20060241138A1公开(公告)日: 2006-10-26
- 发明人: Magnus Pfahl , Catherine Tachdjian , Hussien Al-Shamma , Andrea Giachino , Karine Jakubowicz-Jaillardon , Jianhua Guo , Mohamed Boudjelal , James Zapf
- 申请人: Magnus Pfahl , Catherine Tachdjian , Hussien Al-Shamma , Andrea Giachino , Karine Jakubowicz-Jaillardon , Jianhua Guo , Mohamed Boudjelal , James Zapf
- 主分类号: A61K31/4709
- IPC分类号: A61K31/4709 ; A61K31/427 ; A61K31/4178
摘要:
The present invention relates to methods of treating breast cancer, diabetes, and/or related metabolic disorders with certain substituted heterocycles of Formula (200), wherein B, H, I, J and K together with the Ar5 form a ring containing at least one amide residue, and W, X, Y and Z together form a 2,4-thiazolidinedione, 2-thioxo-thiazolidine-4-one, 2,4-imidazolidinedione or 2-thioxo-imidazolidine-4-one residue; or a pharmaceutically acceptable salt thereof.