- 专利标题: Imidazoline derivatives having CB1-antagonistic activity
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申请号: US11058168申请日: 2005-02-16
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公开(公告)号: US20060241152A9公开(公告)日: 2006-10-26
- 发明人: Josephus Lange , Cornelis Kruse , Herman Van Stuivenberg
- 申请人: Josephus Lange , Cornelis Kruse , Herman Van Stuivenberg
- 专利权人: SOLVAY PHARMACEUTICALS B.V.
- 当前专利权人: SOLVAY PHARMACEUTICALS B.V.
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/4178 ; C07D43/02
摘要:
The present invention relates to 1,2,4-tri-substituted imidazoline derivatives, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said imidazoline derivatives, to methods for the preparation of these intermediates, to pharmaceutical compositions containing one or more of these imidazoline derivatives as active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.
公开/授权文献
- US07173044B2 Imidazoline derivatives having CB1-antagonistic activity 公开/授权日:2007-02-06