发明申请
- 专利标题： Hetero type pentamer recombinant vaccine
- 专利标题（中）： 异种五聚体重组疫苗
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申请号： US10565595申请日： 2004-07-23
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公开(公告)号： US20060246087A1公开(公告)日： 2006-11-02
- 发明人: Takeshi Arakawa , Masanao Kikukawa , Isao Shimabukuro , Masayuki Tadano , Yasunobu Matsumoto , Naotoshi Tsuji , Yoshiya Sato
- 申请人： Takeshi Arakawa , Masanao Kikukawa , Isao Shimabukuro , Masayuki Tadano , Yasunobu Matsumoto , Naotoshi Tsuji , Yoshiya Sato
- 申请人地址： JP Okinawa 901-1202 JP Okinawa 903-0213
- 专利权人： ADVANCED MEDICAL BIO. SCIENCE INSTITUTE CO.LTD.,UNIVERSITY OF THE RYUKYUS
- 当前专利权人： ADVANCED MEDICAL BIO. SCIENCE INSTITUTE CO.LTD.,UNIVERSITY OF THE RYUKYUS
- 当前专利权人地址： JP Okinawa 901-1202 JP Okinawa 903-0213
- 优先权： JP2003-279156 20030724; JP2003-412053 20031210
- 国际申请： PCT/JP04/10459 WO 20040723
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; C07H21/04 ; C12N15/86 ; C07K14/18
摘要：
A heteropentamer composed of a fusion monomer (32) comprising a fusion protein of an antigenic amino acid sequence and an amino acid sequence of a monomer of a mucous membrane-binding protein and a nonfusion monomer (20) of an amino acid sequence of a monomer of a mucous membrane-binding protein. A homopentamer composed of a fusion monomer including a fusion protein of an antigen derived from an envelope protein of Japanese encephalitis virus and an amino acid sequence of a monomer of a mucous membrane-binding protein. These heteropentamer and the homopentamer can be used as a vaccine.
公开/授权文献
- US07544361B2 Hetero type pentamer recombinant vaccine 公开/授权日：2009-06-09
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