A thermoplastic foam composite has at least one active agent layer, which includes active agent materials that are coated with a thermal-sticky polymer, and which is bonded to at least one surface of a soft, flexible, absorbent thermoplastic foam layer. The thermoplastic foam composite can exhibit desirable active agent properties while maintaining sufficient integrity, absorbency, and/or flexibility for specific applications. In some aspects, an adhesive can be utilized to assist with bonding the active agent layer to the thermoplastic foam layer. The thermoplastic foam composite can be utilized as an article, such as a packaging, wiper, towel, or insulation product, or can be incorporated as a component into a variety of other articles, including personal care articles, health/medical articles, and household/industrial articles, for example.