发明申请
US20060251735A1 Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins 有权
用于通过与骨形态发生蛋白结合的氧固醇来增强骨形成的药剂和方法

  • 专利标题: Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
  • 专利标题(中): 用于通过与骨形态发生蛋白结合的氧固醇来增强骨形成的药剂和方法
  • 申请号: US10569994
    申请日: 2004-08-30
  • 公开(公告)号: US20060251735A1
    公开(公告)日: 2006-11-09
  • 发明人: Farhad Parhami
  • 申请人: Farhad Parhami
  • 国际申请: PCT/US04/28162 WO 20040830
  • 主分类号: A61K38/22
  • IPC分类号: A61K38/22 A61K38/18 A61K31/66 A61K31/59 A61K31/56 A61K33/14
Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
摘要:
The present invention discloses agents and methods for inducing osteoblastic cellular differentiation, as well as the use of such agents and methods to treat patients to maintain bone mass, enhance bone formation and/orbone repair. Exemplary agents include oxysterols, alone or in combination with particular oxysterols, or other agents, such as bone morphogenic proteins, known to assist in bone formation. The invention further includes medicaments including oxysterols for the treatment of bone disorders and implants to facilitate bone repair.
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