发明申请
US20060252957A1 Novel malonic acid monomethyl derivatives and production process thereof 失效
新型丙二酸单甲基衍生物及其制备方法

  • 专利标题: Novel malonic acid monomethyl derivatives and production process thereof
  • 专利标题(中): 新型丙二酸单甲基衍生物及其制备方法
  • 申请号: US11486116
    申请日: 2006-07-14
  • 公开(公告)号: US20060252957A1
    公开(公告)日: 2006-11-09
  • 发明人: Satoru NoseKieko SanoTakeshi Hamatani
  • 申请人: Satoru NoseKieko SanoTakeshi Hamatani
  • 优先权: JP2003-409350 20031208
  • 主分类号: C07C69/76
  • IPC分类号: C07C69/76
Novel malonic acid monomethyl derivatives and production process thereof
摘要:
A novel monomethyl malonate derivative is represented by following Formula (I): wherein X is a halogen atom; and Me is methyl group. This compound can be prepared by the steps of (A) reacting a benzyl halide derivative represented by following Formula (II): wherein X and Y may be the same as or different from each other and are each a halogen atom, with dimethyl malonate in the presence of a base to yield a dimethyl malonate derivative represented by following Formula (III): wherein X and Me have the same meanings as defined above; and (B) hydrolyzing the dimethyl malonate derivative of Formula (III). The compound is useful in the production of an indanonecarboxylic acid ester having a halogen atom on the indanone ring.
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