发明申请
- 专利标题: Vaccine
- 专利标题(中): 疫苗
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申请号: US11337733申请日: 2006-01-23
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公开(公告)号: US20060257418A1公开(公告)日: 2006-11-16
- 发明人: Lauren Bakaletz , Joseph Cohen , Guy Dequesne , Yves Lobet
- 申请人: Lauren Bakaletz , Joseph Cohen , Guy Dequesne , Yves Lobet
- 专利权人: SmithKline Beecham Biologicals, s.a.,Ohio State University Research Foundation
- 当前专利权人: SmithKline Beecham Biologicals, s.a.,Ohio State University Research Foundation
- 优先权: GB9812613.9 19980611
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K39/38
摘要:
This invention relates to three newly-identified, distinct groups of antigenic peptides [LB1(f) peptides] from the same region of the P5-like fimbrin protein discovered using sequence data from the fimbrin protein of many Haemophilus influenzae strains. The invention additionally provides chimeric polypeptides that carry one or more representatives of such peptides from different groups and which induce an immunogenic response in animals to Haemophilus influenzae. The peptides and polypeptides of the invention will be useful in vaccine compositions which provide protection against a wide range of H. influenzae strains.
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