发明申请
- 专利标题： Ghrelin binding nucleic acids
- 专利标题（中）： 生长素释放肽结合核酸
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申请号： US11400459申请日： 2006-04-07
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公开(公告)号： US20060258607A1公开(公告)日： 2006-11-16
- 发明人: Florian Jarosch , Dirk Eulberg , Christian Maasch , Steffen Helmling , Sven Klussmann
- 申请人： Florian Jarosch , Dirk Eulberg , Christian Maasch , Steffen Helmling , Sven Klussmann
- 申请人地址： DE Berlin
- 专利权人： NOXXON Pharma AG
- 当前专利权人： NOXXON Pharma AG
- 当前专利权人地址： DE Berlin
- 优先权： EP05007795.7 20050408
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12Q1/68 ; C07H21/04
摘要：
The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second stretch Box B, whereby the first stretch Box A comprises about 25 consecutive nucleotides, the second stretch Box B comprises about six to eight consecutive nucleotides, whereby a 3′-terminal stretch of nucleotides of the first stretch Box A hybridises with the second stretch Box B, whereby upon hybridisation a first double-stranded structure is formed, whereby such first double-stranded structure comprises a bulge.
公开/授权文献
- US08101734B2 Ghrelin binding nucleic acids 公开/授权日：2012-01-24
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