发明申请
- 专利标题： Antibodies against IL-13 receptor alpha1 and uses thereof
- 专利标题（中）： 针对IL-13受体α1的抗体及其用途
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申请号： US11325197申请日： 2006-01-03
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公开(公告)号： US20060263356A1公开(公告)日： 2006-11-23
- 发明人: Josef Endl , Maria Fuentes , Yvo Graus , Adelbert Grossmann , Sebastian Neumann , Paul Parren , Frank Rebers , Joerg Regula , Ralf Schumacher , Stefan Seeber , Jan stracke , Kay-Gunnar Stubenrauch , Jan Van De Winkel , Martine Van Vugt , Sandra Vereecken-Verploegen
- 申请人： Josef Endl , Maria Fuentes , Yvo Graus , Adelbert Grossmann , Sebastian Neumann , Paul Parren , Frank Rebers , Joerg Regula , Ralf Schumacher , Stefan Seeber , Jan stracke , Kay-Gunnar Stubenrauch , Jan Van De Winkel , Martine Van Vugt , Sandra Vereecken-Verploegen
- 优先权： EPEP05000003.3 20050103; EPEP05002229.2 20050203
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07H21/04 ; C12P21/06 ; C12N5/06
摘要：
An antibody binding to IL-13Rα1, inhibiting IL-13 bioactivity and comprising a variable heavy and a variable light chain, characterized in that the variable heavy chain amino acid sequence CDR3 of said antibody is selected from the group consisting of the heavy chain CDR3 sequences of SEQ ID NO: 1, 3, 5, 7 or 9 is useful in the treatment of asthma and allergic diseases.
公开/授权文献
- US07807158B2 Antibodies against IL-13 receptor alpha1 and uses thereof 公开/授权日：2010-10-05
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