发明申请
US20060269613A1 Composition containing nanoparticles containing water-soluble basic drug encpsulated therein
审中-公开
含有包含水溶性碱性药物的纳米颗粒的组合物
- 专利标题: Composition containing nanoparticles containing water-soluble basic drug encpsulated therein
- 专利标题(中): 含有包含水溶性碱性药物的纳米颗粒的组合物
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申请号: US10570819申请日: 2004-09-06
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公开(公告)号: US20060269613A1公开(公告)日: 2006-11-30
- 发明人: Yasuaki Ogawa , Shoko Nagasaki , Chieko Tsuchiya , Sohei Higashi , Hiroyuki Saito
- 申请人: Yasuaki Ogawa , Shoko Nagasaki , Chieko Tsuchiya , Sohei Higashi , Hiroyuki Saito
- 优先权: JP2003-312848 20030904
- 国际申请: PCT/JP04/13256 WO 20040906
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K9/50 ; A61K38/17 ; A61K31/4745
摘要:
A drug and a biodegradable polymer having at least one carboxyl group are encapsulated into nanoparticle which is formed by a block copolymer having a hydrophilic segment and a hydrophobic segment. This invention thus provides a drug-encapsulated nanoparticle which shows an increased in vivo drug-stability.
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