发明申请
US20060270668A1 Methods of synthesizing substituted 3-cyanoquinolines and intermediates thereof
审中-公开
合成取代的3-氰基喹啉的方法及其中间体
- 专利标题： Methods of synthesizing substituted 3-cyanoquinolines and intermediates thereof
- 专利标题（中）： 合成取代的3-氰基喹啉的方法及其中间体
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申请号： US11439984申请日： 2006-05-25
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公开(公告)号： US20060270668A1公开(公告)日： 2006-11-30
- 发明人: Warren Chew , Gloria Cheal , Jacqueline Lunetta
- 申请人： Warren Chew , Gloria Cheal , Jacqueline Lunetta
- 申请人地址： US NJ Madison
- 专利权人： WYETH
- 当前专利权人： WYETH
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/506 ; A61K31/496 ; A61K31/4709 ; C07D413/02 ; C07D403/02
摘要：
The invention is directed to methods of making substituted 3-cyanoquinolines, including compounds according to the following formula: The methods are amenable to large scale manufacture, avoid the use of chromatographic separations, and provide stable, high purity product more efficiently than in the prior art.
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