An iontophoresis device, and a control method thereof, may be capable of increasing movement speed of a drug into a living body and/or may be capable of administering a drug having a high molecular weight. The iontophoresis device may include an active electrode assembly comprising: a first electrode; a drug holding part that receives a current from the first electrode; and a first ion exchange membrane that selectively passes ions of a first polarity, the first ion exchange membrane being placed on a front side of the drug holding part. Drug ions of the first polarity generated by the dissociation of a drug held in the drug holding part may be administered to a living body through the first ion exchange membrane in contact with skin of the living body. The iontophoresis device may include heating means to heat the skin in contact with the first ion exchange membrane.