Invention Application
- Patent Title: Therapeutic agents comprising pro-apoptotic proteins
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Application No.: US11415342Application Date: 2006-05-01
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Publication No.: US20060280749A1Publication Date: 2006-12-14
- Inventor: Michael Rosenblum , Yuying Liu
- Applicant: Michael Rosenblum , Yuying Liu
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07H21/04 ; C12P21/06 ; C07K16/46 ; C07K16/30
Abstract:
The present invention relates to targeted killing of a cell utilizing a chimeric polypeptide comprising a cell-specific targeting moiety and a signal transduction pathway factor. In a preferred embodiment, the signal transduction pathway factor is an apoptosis-inducing factor, such as granzyme B, granzyme A, or Bax.
Public/Granted literature
- US07371723B2 Therapeutic agents comprising pro-apoptotic proteins Public/Granted day:2008-05-13
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