发明申请
- 专利标题： Carboxamide inhibitors of TGFbeta
- 专利标题（中）： TGFbeta的甲酰胺抑制剂
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申请号： US11390980申请日： 2006-03-27
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公开(公告)号： US20060281763A1公开(公告)日： 2006-12-14
- 发明人: Jonathan Axon , Sarvajit Chakravarty , Barry Hart , Glenn McEnroe , Alison Murphy , Karen Pontius , Peijue Sheng , Xiaojing Wang , Shanthi Yellapregada
- 申请人： Jonathan Axon , Sarvajit Chakravarty , Barry Hart , Glenn McEnroe , Alison Murphy , Karen Pontius , Peijue Sheng , Xiaojing Wang , Shanthi Yellapregada
- 主分类号： C07D403/14
- IPC分类号： C07D403/14 ; C07D403/02 ; A61K31/506
摘要：
Certain appropriately substituted forms of pyrimidine having a pyridylamine group at C-4 of the pyrimidine and an amide group on the pyridine ring are useful in the treatment of conditions associated with excessive TGFβ activity.