- 专利标题： Recombinant alpha-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
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申请号： US11429422申请日： 2006-05-05
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公开(公告)号： US20060286087A1公开(公告)日： 2006-12-21
- 发明人: Emil Kakkis , Becky Tanamachi
- 申请人： Emil Kakkis , Becky Tanamachi
- 申请人地址： US CA Novato
- 专利权人： BIOMARIN PHARMACEUTICAL INC.
- 当前专利权人： BIOMARIN PHARMACEUTICAL INC.
- 当前专利权人地址： US CA Novato
- 主分类号： A61K38/47
- IPC分类号： A61K38/47 ; C07H21/04 ; C12P21/06 ; C12N9/36
摘要：
The present invention provides a recombinant α-L-iduronidase and biologically active fragments and mutants thereof, methods to produce and purify this enzyme as well as methods to treat certain genetic disorders including—α-L-iduronidase deficiency and mucopolysaccharidosis I (MPS 1).
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