- 专利标题: Mitotic kinesin inhibitors
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申请号: US10568000申请日: 2004-08-11
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公开(公告)号: US20060287302A1公开(公告)日: 2006-12-21
- 发明人: Paul Coleman , Christopher Cox
- 申请人: Paul Coleman , Christopher Cox
- 国际申请: PCT/US04/26242 WO 20040811
- 主分类号: A61K31/541
- IPC分类号: A61K31/541 ; A61K31/5377 ; A61K31/496 ; A61K31/4025 ; A61K31/454 ; C07D417/14 ; C07D413/14 ; C07D403/14
摘要:
The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention is also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- US07638549B2 Mitotic kinesin inhibitors 公开/授权日:2009-12-29
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