发明申请
US20060287332A1 Melanocortin Receptor-Specific Piperazine and Keto-Piperazine Compounds
有权
黑皮质素受体特异性哌嗪和酮 - 哌嗪化合物
- 专利标题: Melanocortin Receptor-Specific Piperazine and Keto-Piperazine Compounds
- 专利标题(中): 黑皮质素受体特异性哌嗪和酮 - 哌嗪化合物
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申请号: US11464069申请日: 2006-08-11
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公开(公告)号: US20060287332A1公开(公告)日: 2006-12-21
- 发明人: Shubh SHARMA , Yi-Qun SHI , Kevin BURRIS , Zhijun WU , Papireddy PURMA , Yadi Reddy BONUGA
- 申请人: Shubh SHARMA , Yi-Qun SHI , Kevin BURRIS , Zhijun WU , Papireddy PURMA , Yadi Reddy BONUGA
- 申请人地址: US NJ Cranbury
- 专利权人: PALATIN TECHNOLOGIES, INC.
- 当前专利权人: PALATIN TECHNOLOGIES, INC.
- 当前专利权人地址: US NJ Cranbury
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D241/04
摘要:
Melanocortin receptor-specific compounds of the general formula and pharmaceutically acceptable salts thereof, where X, W, J, Q, L1, L2, L3, R1a, R1b, R2a, and R2b are as defined in the specification, and the carbon atom marked with an asterisk can have any stereochemical configuration. Compounds disclosed herein bind to one or more melanocortin receptors and may be an agonist, a partial agonist, an antagonist, an inverse agonist or an antagonist of an inverse agonist as to one or more melanocortin receptors, and may be employed for treatment of one or more melanocortin receptor-associated conditions or disorders, including specifically treatment of obesity and related conditions.