- 专利标题: Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
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申请号: US11194875申请日: 2006-03-30
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公开(公告)号: US20060293383A1公开(公告)日: 2006-12-28
- 发明人: Ellen Codd , Carlos Plata-Salaman , Boyu Zhao
- 申请人: Ellen Codd , Carlos Plata-Salaman , Boyu Zhao
- 主分类号: A61K31/325
- IPC分类号: A61K31/325
摘要:
This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) substantially free of other enantiomers or an enantiomeric mixture wherein an enantiomer of Formula (I) predominates: wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
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