A computer enclosure includes a chassis, a top cover pivotally mounted to the chassis, a side cover pivotally mounted on the chassis, a pair of springs, and a locating member slidably mounted to the side cover. The top cover is formed to have at least one catch thereon. The side cover, the chassis, and the top cover configure a receiving space for accommodating other components. The locating member defines at least one latching opening therein for engaging with the catch. When the top cover is pivoted downward, the catch of the top cover engages in the latching opening of the locating member firmly, thereby interlocking the top cover and the side cover detachably.