发明申请
- 专利标题: Prefoldin 4 in the treatment and diagnosis of cancer
- 专利标题(中): 前列腺素4在治疗和诊断癌症
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申请号: US11471464申请日: 2006-06-19
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公开(公告)号: US20070015724A1公开(公告)日: 2007-01-18
- 发明人: Joe Gray , Graeme Hodgson , Douglas Hanahan , Jeffrey Hager , Oriol Casanovas
- 申请人: Joe Gray , Graeme Hodgson , Douglas Hanahan , Jeffrey Hager , Oriol Casanovas
- 申请人地址: US CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: US CA Oakland
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12Q1/68 ; G01N33/574
摘要:
This invention provides methods employing prefoldin-4 (PFDN-4) nucleic acid and polypeptide sequences to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and/or for prognostic applications. Further, the invention provides methods of identifying inhibitors of PfDN-4 and methods of treating cancer by inhibiting the expression and/or activity of PFDN-4.
公开/授权文献
- US07785813B2 Prefoldin 4 in the treatment and diagnosis of cancer 公开/授权日:2010-08-31