发明申请
- 专利标题： Diaryl ureas with kinase inhibiting activity
- 专利标题（中）： 具有激酶抑制活性的二芳基脲
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申请号： US10571100申请日： 2004-05-19
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公开(公告)号： US20070020704A1公开(公告)日： 2007-01-25
- 发明人: Scott Wilhelm , Jacques Dumas , Gaetan Ladouceur , Mark Lynch , William Scott
- 申请人： Scott Wilhelm , Jacques Dumas , Gaetan Ladouceur , Mark Lynch , William Scott
- 国际申请： PCT/US04/15655 WO 20040519
- 主分类号： G01N33/567
- IPC分类号： G01N33/567 ; C12Q1/37 ; A61K31/165 ; A61K31/16 ; A61K31/66
摘要：
The present invention provides methods of using aryl ureas to treat diseases and conditions associated with signal transduction pathways comprising at least one of raf, VEGFR, PDGFR, p38 and/or FLT-3. The present invention also provides compositions and methods for identifying conditions and diseases which can be modulated with compounds of the present invention. These methods facilitate the selection of subjects who can be efficiently treated with compounds of the present invention. Additionally, the invention provides methods for monitoring subjects who have been administered a compound of the present invention.