发明申请
US20070020741A1 Process for preparing enantiomer-enriched alpha-hydroxycarboxylic acids and amides
审中-公开
制备富含对映异构体的α-羟基羧酸和酰胺的方法
- 专利标题： Process for preparing enantiomer-enriched alpha-hydroxycarboxylic acids and amides
- 专利标题（中）： 制备富含对映异构体的α-羟基羧酸和酰胺的方法
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申请号： US10575386申请日： 2004-10-07
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公开(公告)号： US20070020741A1公开(公告)日： 2007-01-25
- 发明人: Karlheinz Drauz , Stefan Buchholz , Harald Groger
- 申请人： Karlheinz Drauz , Stefan Buchholz , Harald Groger
- 优先权： DE10347888.4 20031010
- 国际申请： PCT/EP04/11183 WO 20041007
- 主分类号： C12P7/40
- IPC分类号： C12P7/40 ; C12N9/80
摘要：
The present invention describes an enzymatic process for preparing enantiomer-enriched α-hydroxycarboxylic acids and amides which comprises, in one step, the conversion of a carbonyl compound to the corresponding acid/amides via the intermediate stage of a cyanohydrin. The invention also provides a reaction system operating in such a way and a whole-cell catalyst that is advantageous for use for this reaction.
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