发明申请
US20070021501A1 Methods of treating epileptogenesis 审中-公开
治疗癫痫发生的方法

  • 专利标题: Methods of treating epileptogenesis
  • 专利标题(中): 治疗癫痫发生的方法
  • 申请号: US11481626
    申请日: 2006-07-06
  • 公开(公告)号: US20070021501A1
    公开(公告)日: 2007-01-25
  • 发明人: Roy TwymanBoyu Zhao
  • 申请人: Roy TwymanBoyu Zhao
  • 主分类号: A61K31/325
  • IPC分类号: A61K31/325
Methods of treating epileptogenesis
摘要:
This invention is directed to methods for preventing, treating, reversing, inhibiting, or arresting epileptogenesis in a subject comprising administering to the subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II), or a pharmaceutically acceptable salt or ester thereof,: wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
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