发明申请
- 专利标题: Neisseria meningitidis antigens and compositions
- 专利标题(中): 脑膜炎奈瑟氏球菌抗原和组合物
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申请号: US11395121申请日: 2006-03-31
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公开(公告)号: US20070026021A1公开(公告)日: 2007-02-01
- 发明人: Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Peterson , Mariagrazia Pizza , Rino Rappuoli , Giulo Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , Craig Venter
- 申请人: Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Peterson , Mariagrazia Pizza , Rino Rappuoli , Giulo Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , Craig Venter
- 申请人地址: IT Siena
- 专利权人: Chiron S.r.I.
- 当前专利权人: Chiron S.r.I.
- 当前专利权人地址: IT Siena
- 主分类号: A61K39/095
- IPC分类号: A61K39/095 ; C07K14/22 ; C07K16/12
摘要:
This invention provides, among other things, protein, polypeptides, and fragments thereof, derived from bacteria Neisseria meningitidis B. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto (e.g., antisense nucleic acids). Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments and/or nucleic acids.